Parents often know when something seems “off” with their child. Maybe it’s a sudden onset of anxiety, obsessive behaviors, or a complete personality shift. When these symptoms appear seemingly overnight, it can be both confusing and frightening. One lesser-known cause of such changes could be PANS or PANDAS—two serious, but treatable, conditions that affect a child’s neurological and behavioral health.
For families in Canada exploring multidisciplinary care, Level Up Wellness Group offers resources and professionals experienced in supporting children through these complex disorders.
What Are PANS and PANDAS?
PANS (Pediatric Acute-onset Neuropsychiatric Syndrome) and PANDAS (Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infections) are conditions that cause sudden-onset neuropsychiatric symptoms in children. They are believed to result from an immune response that affects the brain, leading to severe behavioral and cognitive changes.
PANDAS:
- Specifically triggered by Group A Streptococcus (strep throat).
- Immune system mistakenly attacks healthy brain tissue (especially in the basal ganglia, responsible for movement and behavior).
PANS:
- Similar symptoms as PANDAS but caused by other infections (e.g., Lyme disease, influenza, mycoplasma) or environmental triggers.
- Broader diagnostic criteria than PANDAS.
Common Symptoms of PANS/PANDAS
The most notable aspect of PANS or PANDAS is how suddenly symptoms appear—often within 24–48 hours. They may include:
- Obsessive-compulsive behaviors (OCD)
- Severe anxiety or panic attacks
- Tics or motor abnormalities
- Mood swings or depression
- Aggression or irritability
- Regression in academic skills
- Food restriction or eating disorders
- Sleep disturbances
These symptoms can be terrifying for families, especially when a previously healthy child transforms almost overnight.
How Are PANS and PANDAS Diagnosed?
Diagnosing PANS and PANDAS can be tricky, as they often mimic other neurological or psychiatric disorders. A qualified practitioner will:
- Review your child’s medical history, especially recent infections.
- Assess sudden-onset behavioral changes.
- Conduct lab tests for strep antibodies, inflammatory markers, or autoimmune responses.
- Rule out other psychiatric conditions or developmental disorders.
Clinics offering multidisciplinary evaluations, such as Level Up Wellness Group, often bring together pediatricians, neurologists, psychologists, and naturopathic doctors to get a more comprehensive picture.
What Causes the Sudden Behavior Shift?
When the immune system responds to an infection, it releases antibodies to fight off invaders. In children with PANS or PANDAS, these antibodies can mistakenly attack healthy brain cells, particularly in areas responsible for emotion, motor control, and decision-making.
This autoimmune reaction is what causes the sudden behavioral changes. Over time, if left untreated, the inflammation can persist and cause lasting symptoms.
Tip: Watch for Patterned Flare-Ups
One of the most important signs of PANS/PANDAS is the episodic nature of the symptoms. Parents often report that symptoms come and go—especially after the child is exposed to infections, stress, or even allergens.
Keeping a symptom journal can help your care team recognize patterns and identify possible triggers.
Treatment Options for PANS and PANDAS
Treatment typically involves a multifaceted approach. The goal is to:
- Remove the infection
- Control inflammation
- Manage symptoms
- Strengthen immune function
Here’s a breakdown of commonly used therapies:
1. Antibiotics
- Used to eliminate strep or other bacterial infections.
- Must be prescribed carefully and often long-term.
2. Anti-Inflammatory Medications
- Such as ibuprofen or steroids, to reduce brain inflammation.
- Can bring rapid relief when symptoms are severe.
3. Cognitive Behavioral Therapy (CBT)
- Especially for OCD, anxiety, or behavioral challenges.
- Helps children build emotional regulation skills.
4. Nutritional Support and Detoxification
- Functional medicine often includes dietary interventions.
- May use supplements like omega-3 fatty acids, vitamin D, or probiotics.
5. Immune-Modulating Therapies
- In complex or recurring cases, treatments like IVIG (intravenous immunoglobulin) may be considered.
- Always requires close medical supervision.
The Role of Multidisciplinary Clinics
PANS and PANDAS affect every part of a child’s life—mental, emotional, behavioral, and physical. That’s why many parents find relief by working with a team-based clinic that offers various forms of therapy under one roof.
At clinics like Level Up Wellness Group, families can access:
- Medical diagnostics and lab testing
- Pediatric counseling and psychotherapy
- Nutritional consultations
- Naturopathic and functional medicine
- Parent coaching and education
This integrated care model not only supports the child but also helps caregivers navigate the complexity of treatment and recovery.
What Parents Can Do at Home
While professional care is essential, home support plays a huge role in recovery. Here are some strategies to support your child:
Build a Calm Routine
Children with PANS/PANDAS thrive in predictable environments. Limit exposure to stress, overstimulation, and inconsistent schedules.
Prioritize Sleep
Brain healing requires quality rest. Establish a calming bedtime routine and minimize screens before sleep.
Reduce Inflammatory Foods
Avoid processed foods, dyes, and high-sugar snacks. Instead, focus on nutrient-rich meals that support immune health.
Use Gentle Language
Children often feel confused or scared about their own behavior. Use non-judgmental language, validate their experience, and remind them that help is available.
Support for Families
One of the biggest challenges families face is the emotional toll. Watching your child struggle—especially when few people understand the condition—can feel isolating.
Look for:
- Online and local support groups
- Educational webinars or workshops
- Parent counseling or coaching
Knowing you’re not alone can make all the difference.
Long-Term Outlook
The good news? Recovery is possible. Many children with early diagnosis and comprehensive treatment go on to lead healthy, happy lives. Symptoms may recur occasionally, but with proper management, they often diminish in severity over time.
The key is staying informed, proactive, and connected to a trusted care team.
Final Thoughts
PANS and PANDAS can feel like a whirlwind—but knowledge and support can help ground you. If your child has recently shown sudden behavioral changes after an illness, it’s worth exploring the possibility of an autoimmune connection.
With multidisciplinary support from places like Level Up Wellness Group, families can find answers, relief, and hope. Your child’s brain and body are capable of healing—with the right tools and guidance, you’re already on the path forward.
FAQs
1. What’s the difference between PANS and PANDAS?
PANDAS is triggered specifically by a streptococcal (strep) infection, while PANS can result from various infections or environmental factors. Both cause sudden neuropsychiatric symptoms.
2. How quickly do symptoms appear in PANS/PANDAS?
Symptoms often appear within 24 to 48 hours, marking a sharp and noticeable change in behavior, mood, or cognitive ability.
3. Can PANS or PANDAS go away on its own?
While some mild cases may improve over time, medical treatment is crucial to prevent long-term neurological damage and reduce the risk of recurring episodes.
4. Are antibiotics always necessary for treatment?
For PANDAS, antibiotics are typically required to address the underlying strep infection. In PANS, antibiotics may be used depending on the trigger but are often combined with other therapies.
5. How can parents support a child with PANS/PANDAS at home?
Parents can support healing by creating a calm environment, prioritizing sleep, using anti-inflammatory nutrition, and working closely with a multidisciplinary care team.
